E-AB-52117
ROCK2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52117
- Additional Names:
- KIAA0619,Rho associated,Rho associated coiled coil containing protein kinase 2,Rho associated protein kinase 2,Rho kinase 2,Rho-associa,Rho-associated,coiled coil containing protein kinase II,coiled-coil-containing protein kinase 2,p164 ROCK 2,p164 ROCK-2
- Application:
- WB
- Concentration:
- 0.78 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Fusion protein of human ROCK2
- Uniprot:
- O75116
- Synonyms:
- p164 ROCK-2;Rho kinase 2;rho-associated protein kinase 2;Rho-associated, coiled-coil-containing protein kinase 2;rho-associated, coiled-coil-containing protein kinase II;ROCK-II
- Extra Details:
- The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of ADD1, BRCA2, CNN1, EZR, DPYSL2, EP300, MSN, MYL9/MLC2, NPM1, RDX, PPP1R12A and VIM. Phosphorylates SORL1 and IRF4.
- Shipping Conditions:
- Blue Ice