E-AB-52051
ITPR2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-52051
- Additional Names:
- 4,5-trisphosphate receptor,5-trisphosphate receptor type 2,IP3 R2,IP3 receptor,IP3 receptor isoform 2,IP3R 2,IP3R2,ITPR 2,ITPR2,Inositol 1,Inositol 1 4 5 trisphosphate receptor type 2,Inositol 145 trisphosphate receptor type 2,InsP3 R2,InsP3R2,Itpr2,Typ
- Application:
- IHC
- Concentration:
- 1.74 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ITPR2
- Uniprot:
- Q14571
- Synonyms:
- ANHD;CFAP48;cilia and flagella associated protein 48;inositol 1,4,5-trisphosphate receptor type 2;INSP3R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;Type 2 inositol 1,4,5-trisphosphate receptor;type 2 InsP3 receptor
- Extra Details:
- Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
- Shipping Conditions:
- Blue Ice