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E-AB-40572

CXCL4 Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40572
Additional Names:
PF-4, Platelet factor 4, SCYB4,CXCL4
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human CXCL4 protein expressed by E.coli.
Uniprot:
P02776
Synonyms:
C-X-C motif chemokine 4;chemokine (C-X-C motif) ligand 4;CXCL4;iroplact;oncostatin-A;PF-4;platelet factor 4;SCYB4
Extra Details:
CXCL4/PF4 is a secreted chemokine that is expressed by megakaryocytes and restrains the coagulation cascade. It is released by activated platelets and regulates Thrombin/Thrombomodulin complexes, activated Protein C (APC), Coagulation Factor Xa, and Fibrin. The anticoagulant heparin neutralizes CXCL4 procoagulant effects. Complexes of heparin and CXCL4 trigger antibody formation that causes the pathological syndrome HITT
Shipping Conditions:
Blue Ice