Angiotensinogen Polyclonal Antibody

Size

£120.60

Was £134.00

SKU:: E-AB-40478
Additional Names:: A, AGT, AI265500, Alpha 1 antiproteinase antitrypsin, Ang, Ang I, Ang II, Ang III, AngII, Angiotensin I, Angiotensin II, Angiotensin III, Angiotensin-3, Angiotensinogen, Angiotensinogen (PAT),Aangiotensinogen (serpin peptidase inhibitor clade A member 8)
Application:: IHC, WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Mouse, Rat
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Mouse Angiotensinogen protein
Uniprot:: P11859
Synonyms:: Serpin A8
Extra Details:: Angiotensinogen is a precursor of angiotensin II (Ang II),is expressed and synthesized largely in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. It has a key role in mediating vascular constriction and regulating salt and fluid homeostasis. The resulting product,angiotensin I,is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. Mutations in this gene are associated with susceptibility to essential hypertension,and can cause renal tubular dysgenesis,a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation,and inflammatory bowel disease.