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E-AB-40473

GPNMB Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40473
Additional Names:
Glycoprotein nmb like protein, Gpnmb, HGFIN, NMB, Osteoactivin, Transmembrane glycoprotein, Transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB,Glycoprotein nmb
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human Transmembrane glycoprotein NMB protein
Uniprot:
Q14956
Synonyms:
glycoprotein (transmembrane) nmb;glycoprotein nmb-like protein;glycoprotein nonmetastatic melanoma protein B;hematopoietic growth factor inducible neurokinin-1 type;HGFIN;NMB;osteoactivin;PLCA3;transmembrane glycoprotein HGFIN;transmembrane glycoprotein NMB
Extra Details:
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice