E-AB-40459
S100A4 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- E-AB-40459
- Additional Names:
- 42A, CAPL, Calvasculin, FSP1, Fibroblast specific protein 1, Leukemia multidrug resistance associated protein, MTS1, Malignant transformation suppression 1, Metastasin, OTTHUMP00000015467, OTTHUMP00000015468, P9KA, PEL98, calcium Placental protein,18A2
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Mouse Protein S100-A4 protein
- Uniprot:
- P07091
- Synonyms:
- 18A;18A2;42a;C;cal;calvasculin;Capl;Fibroblast-specific protein 1;FS;FSp1;meta;metastasin;metastatic cell protein;Mts;Mts1;PeL;PeL98;pk;pk9a;placental calcium-binding protein;protein 18A2;protein Mts1;protein S100-A4;S100 calcium-binding protein A4
- Extra Details:
- S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
- Shipping Conditions:
- Blue Ice