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E-AB-40412

FGG Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40412
Additional Names:
Fibrinogen gamma chain, Fibrinogen gamma polypeptide,FGG
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Mouse Fibrinogen gamma chain protein
Uniprot:
Q8VCM7
Synonyms:
3010002H13Rik;AI256424;fibrinogen gamma chain;fibrinogen, gamma polypeptide
Extra Details:
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice