FGB Polyclonal Antibody

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£120.60

Was £134.00

SKU:: E-AB-40405
Additional Names:: Epididymis Secretory Sperm Binding Protein Li 78p, FGB, Fibrinogen beta chain, HEL-S-78p,Beta fibrinogen
Application:: IHC, WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Rat Fibrinogen beta chain protein
Uniprot:: P14480
Synonyms:: Ab1-181;Ab1-216;Ac1-581;beta-fibrinogen;fibrinogen beta chain;fibrinogen, B beta polypeptide;fibrinogen, beta polypeptide;liver regeneration-related protein LRRG036/LRRG043/LRRG189
Extra Details:: The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia and thrombotic tendency.