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E-AB-40344

IL6R Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40344
Additional Names:
Membrane glycoprotein,CD126,gp80,IL6Q,IL-6R,IL-6R 1,IL-6R subunit alpha,IL-6R-1,IL6RA,IL-6RA,IL-6R-Alpha,IL6RQ,Interleukin-6 receptor subunit alpha,Membrane glycoprotein 80,IL6R,IL-6R&amp,alpha,alpha,CD 126,CD126 antigen,IL 6R,IL 6R 1,IL 6R alpha,IL-6 receptor alpha chain,IL-6 receptor subunit alpha,IL-6R 1 Membrane glycoprotein 80 (gp80),Interleukin 6 receptor,MGC30256
Application:
IHC, WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human Interleukin-6 receptor subunit alpha protein
Uniprot:
P08887
Synonyms:
CD126;CD126 antigen;gp80;HIES5;IL-1Ra;IL-6 receptor subunit alpha;IL-6R;IL-6R 1;IL-6R-1;IL-6RA;IL6Q;IL6QTL;IL6RA;IL6RQ;interleukin-6 receptor subunit alpha;membrane glycoprotein 80
Extra Details:
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
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Blue Ice