EIF4EBP1 Polyclonal Antibody

Size

£120.60

Was £134.00

SKU:: E-AB-40327
Additional Names:: 4E-BP1,4EBP1,BP 1,Eif4ebp1,Eukaryotic translation initiation factor 4E-binding protein 1,PHAS-I,PHASI,Phosphorylated heat- and acid-stable protein regulated by insulin 1,eIF4E binding protein 1,eIF4E-binding protein 1
Application:: IHC
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 1 protein
Uniprot:: Q13541
Synonyms:: 4E-BP1;4EBP1;BP-1;eIF4E-binding protein 1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I;phosphorylated heat- and acid-stable protein regulated by insulin 1
Extra Details:: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1),is a member of 4EBPs family,which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E,thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors,hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1,alpha,beta and gamma.