AFP Polyclonal Antibody

Size

£120.60

Was £134.00

SKU:: E-AB-40293
Additional Names:: AFPD, Alpha fetoglobulin, Alpha fetoprotein precursor, Alpha-1-fetoprotein, FETA, HPAFP, Hereditary persistence of alpha fetoprotein,Afp
Application:: IHC, WB, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Mouse Afp protein expressed by E.coli
Uniprot:: P02772
Synonyms:: alpha-1-fetoprotein;alpha-fetoglobulin;alpha-fetoprotein;alpha-foetoprotein
Extra Details:: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.