E-AB-40255
AIFM1 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- E-AB-40255
- Additional Names:
- 1,AIFM1,Apoptosis inducing factor,Apoptosis inducing factor 1,Apoptosis-inducing factor 1,CMTX4,COWCK,COXPD6,Harlequin,Hq,MGC111425,MGC5706,Neuropathy,axonal motor-s,mAIF,mitochondrial,mitochondrion associated
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Rat Apoptosis-inducing factor 1, mitochondrial protein
- Uniprot:
- Q9JM53
- Synonyms:
- Aif;apoptosis-inducing factor 1, mitochondrial;apoptosis-inducing factor 1, mitochondrial-like;apoptosis-inducing factor, mitochondrion-associated 1;Pdcd8;programmed cell death 8 (apoptosis-inducing factor);programmed cell death protein 8
- Extra Details:
- This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells.Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation.In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy.Alternative splicing results in multiple transcript variants.A related pseudogene has been identified on chromosome 10.
- Shipping Conditions:
- Blue Ice