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E-AB-40245

RAC2 Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40245
Additional Names:
small GTP binding protein Rac2),EN 7,GX,HSPC 022,HSPC022,RAC 2,Ras related C3 botulinum toxin substrate 2,Ras related C3 botulinum toxin substrate 3,Ras related C3 botulinum toxin substrate 3 (rho family,Rho family small GTP binding protein Rac,p21 Rac 2
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human Ras-related C3 botulinum toxin substrate 2 protien
Uniprot:
P15153
Synonyms:
EN-7;Gx;HSPC022;IMD73A;IMD73B;IMD73C;p21-Rac2;ras-related C3 botulinum toxin substrate 2;ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2);Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2);small G protein
Extra Details:
RAC2,also named as GX,belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses,such as secretory processes,phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.
Shipping Conditions:
Blue Ice