E-AB-40230
MCM3 Polyclonal Antibody
Size
£120.60
Was £134.00
- SKU:
- E-AB-40230
- Additional Names:
- Cervical cancer proto oncogene 5,DNA polymerase alpha holoenzyme associated P1,HCC 5,HCC5,Human cervical cancer proto oncogene 5,MCM 3,MGC1157,Minichromosome maintenance complex component 3,P1 MCM3,P1 h,P1.h,Replication licensing fa,hRlf beta subunit,p102
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human DNA replication licensing factor MCM3 protein
- Uniprot:
- P25205
- Synonyms:
- cervical cancer proto-oncogene 5;DNA polymerase alpha holoenzyme-associated protein P1;DNA replication factor MCM3;DNA replication licensing factor MCM3;HCC5;hRlf beta subunit;MCM3 minichromosome maintenance deficient 3;minichromosome maintenance deficient 3;P1-MCM3;P1.h;p102;replication licensing factor, beta subunit;RLF subunit beta;RLFB
- Extra Details:
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice