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E-AB-40046

AIMP2 Polyclonal Antibody

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£120.60

Was £134.00

SKU:
E-AB-40046
Additional Names:
AIMP2,ARS interacting multi functional protein 2,Aimp2,Aminoacyl tRNA synthase complex-interacting multifunctional protein 2,Aminoacyl tRNA synthetase complex interacting multifunctional protein 2,JTV 1,JTV 1 protein,JTV1,JTV1 gene,Multisynthase complex a
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 protein
Uniprot:
Q13155
Synonyms:
aminoacyl tRNA synthase complex-interacting multifunctional protein 2;ARS-interacting multi-functional protein 2;HLD17;JTV-1;JTV1;multisynthase complex auxiliary component p38;multisynthetase complex auxiliary component p38;P38;protein JTV-1
Extra Details:
Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
Shipping Conditions:
Blue Ice