E-AB-33231
WNT1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-33231
- Additional Names:
- BMND16,INT1,OI15,Proto oncogene protein Wnt 1,Proto-oncogene Int-1 homolog,Proto-oncogene Wnt-1,WNT1,Wingless type MMTV integration site family member 1,Wnt 1,member 1 (oncogene INT1),oncogene Int1,wingless-type MMTV integration site family,wnt1
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from the C-terminal region of human Wnt-1
- Uniprot:
- P04628
- Synonyms:
- BMND16;INT1;OI15;proto-oncogene Int-1 homolog;proto-oncogene Wnt-1;wingless-type MMTV integration site family member 1;wingless-type MMTV integration site family, member 1 (oncogene INT1)
- Extra Details:
- The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is very conserved in evolution, and the protein encoded by this gene is known to be 98% identical to the mouse Wnt1 protein at the amino acid level. The studies in mouse indicate that the Wnt1 protein functions in the induction of the mesencephalon and cerebellum. This gene was originally considered as a candidate gene for Joubert syndrome, an autosomal recessive disorder with cerebellar hypoplasia as a leading feature. However, further studies suggested that the gene mutations might not have a significant role in Joubert syndrome. This gene is clustered with another family member, WNT10B, in the chromosome 12q13 region.
- Shipping Conditions:
- Blue Ice