E-AB-32840
RYR2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-32840
- Additional Names:
- ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,RYR-2,RYR2,RyR,RyR2,Ryanodine receptor 2,Type 2 ryanodine receptor,VTSIP,hRYR-2,ryanodine receptor 2 (cardiac)
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.
- Uniprot:
- Q92736
- Synonyms:
- ARVC2;ARVD2;Cardiac muscle ryanodine receptor;cardiac muscle ryanodine receptor-calcium release channel;cardiac-type ryanodine receptor;islet-type ryanodine receptor;kidney-type ryanodine receptor;ryanodine receptor 2;ryanodine receptor 2 (cardiac);RyR;RYR-2;type 2 ryanodine receptor;VACRDS;VTSIP
- Extra Details:
- This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.
- Shipping Conditions:
- Blue Ice