E-AB-32226
NFK KappaB-p105/p50 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-32226
- Additional Names:
- DKFZp686C01211,DNA binding factor KBF1,DNA binding factor KBF1 EBP1,DNA-binding factor KBF1,EBP 1,EBP-1,EBP1,KBF1,MGC54151,NF kB1,NF kappa B,NF kappaB,NF kappabeta,NFKB 1,NFKB p105,NFKB p50,NFKB1,NFkappaB,Nfkb1,Nuclear factor kappa B DNA binding subu,nf b
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human NFK KappaB-p105/p50 around the non-phosphorylation site of Ser337.
- Uniprot:
- P19838
- Synonyms:
- CVID12;DNA-binding factor KBF1;EBP-1;KBF1;NF-kappa-B1;NF-kappaB;NF-kappabeta;NF-kB;NF-kB1;NFkappaB;NFKB-p105;NFKB-p50;nuclear factor kappa-B DNA binding subunit;nuclear factor NF-kappa-B p105 subunit;nuclear factor NF-kappa-B p50 subunit;nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
- Extra Details:
- NFkB is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. Activated NFkB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFkB has been associated with a number of inflammatory diseases while persistent inhibition of NFkB leads to inappropriate immune cell development or delayed cell growth. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing. This antibody can bind both p105 and p50 isoforms of NFKB1.
- Shipping Conditions:
- Blue Ice