E-AB-31899
LMNA Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-31899
- Additional Names:
- 70 kDa lamin,CDCD1,CDDC,CMD1A,CMT2B1,Cardiomyopathy dilated 1A (autosomal dominant),EMD2,FPL,FPLD,FPLD2,HGPS,IDC,LDP1,LFP,LGMD1B,LMN 1,LMN A,Lamin,Lamin A,Lamin A/C,Lamin A/C like 1,Lamin C,Lamin-A/C,Limb girdle muscular dystrophy 1B (autosomal dominant)
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser392.
- Uniprot:
- P02545
- Synonyms:
- 70 kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;epididymis secretory sperm binding protein;FPL;FPLD;FPLD2;HGPS;IDC;lamin;lamin A/C-like 1;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;mandibuloacral dysplasia type A;prelamin-A/C;PRO1;renal carcinoma antigen NY-REN-32
- Extra Details:
- The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice