E-AB-31647
HDAC5 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-31647
- Additional Names:
- Antigen NY CO 9,Antigen NY-CO-9,HD5,HDAC 5,HDAC5,Histone deacetylase 5,NY CO 9
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human HDAC5 around the non-phosphorylation site of Ser498.
- Uniprot:
- Q9UQL6
- Synonyms:
- antigen NY-CO-9;HD5;histone deacetylase 5;NY-CO-9
- Extra Details:
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors.
- Shipping Conditions:
- Blue Ice