E-AB-31646
HDAC4 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-31646
- Additional Names:
- AHO3,BDMR,EC 3.5.1.98,HA6116,HD 4,HD4,HDAC 4,HDAC A,HDAC4,HDACA,Histone Deacetylase A,Histone deacetylase 4,KIAA0288
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human HDAC4 around the non-phosphorylation site of Ser632.
- Uniprot:
- P56524
- Synonyms:
- AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA;histone deacetylase 4;histone deacetylase A
- Extra Details:
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
- Shipping Conditions:
- Blue Ice