E-AB-31644
HDAC2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-31644
- Additional Names:
- D10Wsu179e,HD 2,HD2,HDAC 2,HDAC2,Hdac2,Histone deacetylase 2,Histone deacetylase 2 (HD2),OTTHUMP00000017046,OTTHUMP00000227077,OTTHUMP00000227078,RPD3,YAF1,YY1 associated factor 1,YY1 transcription factor binding pro,transcriptional regulator homolog RPD3
- Application:
- IHC, WB, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.
- Uniprot:
- Q92769
- Synonyms:
- HD2;histone deacetylase 2;KDAC2;RPD3;transcriptional regulator homolog RPD3;YAF1;YY1-associated factor 1
- Extra Details:
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
- Shipping Conditions:
- Blue Ice