EIF2 alpha Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-31295
Additional Names:: EIF 2,EIF 2 alpha,EIF 2A,EIF 2alpha,EIF-2alpha,EIF2,EIF2 alpha,EIF2A,EIF2S1,Eukaryotic translation initiation fa,Eukaryotic translation initiation factor 2 subunit 1 alpha,Eukaryotic translation initiation factor 2 subunit 1 alpha 35kDa,eIF-2-alpha,eIF-2A
Application:: IHC, WB, IHC-P, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:: Synthesized peptide derived from human eIF2A Alpha around the non-phosphorylation site of Ser51.
Uniprot:: P05198
Synonyms:: EIF-2;eIF-2-alpha;EIF-2A;EIF-2alpha;EIF2;EIF2A;eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Extra Details:: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins.