E-AB-30760
CASP9 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-30760
- Additional Names:
- APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,Caspase 9 Dominant Negative,Caspase 9 apoptosis related cysteine peptidase,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human Caspase-9 around the non-phosphorylation site of Thr125.
- Uniprot:
- P55211
- Synonyms:
- APAF-3;APAF3;apoptotic protease activating factor 3;apoptotic protease MCH-6;Apoptotic protease-activating factor 3;caspase 9, apoptosis-related cysteine peptidase;caspase-9;ICE-LAP6;ICE-like apoptotic protease 6;MCH6;PPP1R56;protein phosphatase 1, regulatory subunit 56
- Extra Details:
- Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
- Shipping Conditions:
- Blue Ice