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E-AB-30758

CASP7 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-30758
Additional Names:
Apoptotic protease MCH3,Apoptotic protease Mch-3,CASP-7,CASP7,CMH 1,CMH-1,CMH1,Caspase 7,Caspase 7 apoptosis related cysteine peptidase,Caspase-7 subunit p11,Caspase7,ICE LAP3,ICE-LAP3,ICE-like apoptotic protease 3,LICE2,MCH3
Application:
IHC, WB, IHC-P, ICC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthesized peptide derived from the N-terminal region of human Caspase-7.
Uniprot:
P55210
Synonyms:
apoptotic protease MCH-3;CASP-7;caspase 7, apoptosis-related cysteine peptidase;caspase 7, apoptosis-related cysteine protease;caspase-7;CMH-1;ICE-LAP3;ICE-like apoptotic protease 3;LICE2;MCH3
Extra Details:
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Overexpression promotes programmed cell death.
Shipping Conditions:
Blue Ice