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E-AB-30582

PYCARD Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-30582
Additional Names:
ASC,Apoptosis associated speck like protein containing a CARD,Apoptosis-associated speck-like protein containing a CARD,CARD 5,CARD5,Caspase recruitment domain containing protein 5,Caspase recruitment domain protein 5,Caspase recruitment domain-contai
Application:
IHC, WB, IHC-P, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthesized peptide derived from the N-terminal region of human ASC
Uniprot:
Q9ULZ3
Synonyms:
apoptosis-associated speck-like protein containing a CARD;ASC;CARD5;caspase recruitment domain-containing protein 5;PYD and CARD domain-containing protein;target of methylation-induced silencing 1;TMS;TMS-1;TMS1
Extra Details:
Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Shipping Conditions:
Blue Ice