E-AB-30491
AMPK alpha1/2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-30491
- Additional Names:
- 5'-AMP-activated protein kinase catalytic subunit alpha-1,ACACA kinase,AMPK,AMPK subunit alpha-1,AMPK1,Acetyl-CoA carboxylase kinase,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA1,PRKAA2,Tau-protein kinase PRKAA1
- Application:
- IHC, WB, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human AMPKA Alpha1/2 around the non-phosphorylation site of Thr183/172.
- Uniprot:
- P54646, Q13131
- Synonyms:
- 5'-AMP-activated protein kinase catalytic subunit alpha-1;5'-AMP-activated protein kinase catalytic subunit alpha-2;5'-AMP-activated protein kinase, catalytic alpha-1 chain;5'-AMP-activated protein kinase, catalytic alpha-2 chain;ACACA kinase;acetyl-CoA carboxylase kinase;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase alpha-2 subunit variant 2;AMP-activated protein kinase alpha-2 subunit variant 3;AMP-activated protein kinase, catalytic, alpha-1;AMPK;AMPK alpha 1;AMPK alpha 2;AMPK subunit alpha-1;AMPK subunit alpha-2;AMPK-alpha-2 chain;AMPK, alpha, 1;AMPK2;AMPKa1;AMPKa2;head maturation protease;HMGCR kinase;HWC90_gp38;hydroxymethylglutaryl-CoA reductase kinase;laban61_gp038;PRKAA;protein kinase, AMP-activated, alpha 1 catalytic subunit;protein kinase, AMP-activated, alpha 2 catalytic subunit;tau-protein kinase PRKAA1
- Extra Details:
- AMPK (for 5'-AMP-activated protein kinase) is a heterotrimeric complex comprising a catalytic A Alpha subunit and regulatory B Beta and G Gamma subunits. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is activated by high AMP and low ATP through a mechanism involving allosteric regulation, promotion of phosphorylation by an upstream protein kinase known as AMPK kinase, and inhibition of dephosphorylation.Activated AMPK can phosphorylate and regulate in vivo hydroxymethylglutaryl-CoA reductase and acetyl-CoA carboxylase, which are key regulatory enzymes of sterol synthesis and fatty acid synthesis, respectively.
- Shipping Conditions:
- Blue Ice