IDH1 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-30163
Additional Names:: Cytosolic NADP isocitrate dehydrogenase,Cytosolic NADP-isocitrate dehydrogenase,Epididymis luminal protein 216,Epididymis secretory protein Li 26,HEL-216,HEL-S-26,ICDH,IDCD,IDH,IDH1,IDHC,IDP,IDPC,Isocitrate d,Isocitrate dehydrogenase (NADP(+)) 1 cytosolic
Application:: IHC, WB, IHC-P
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:: Synthesized peptide derived from the N-terminal region of human IDH1.
Uniprot:: O75874
Synonyms:: Cytosolic NADP-isocitrate dehydrogenase;epididymis luminal protein 216;epididymis secretory protein Li 26;epididymis secretory sperm binding protein;HEL-216;HEL-S-26;IDCD;IDH;IDP;IDPC;isocitrate dehydrogenase (NADP(+)) 1, cytosolic;isocitrate dehydrogenase [NADP] cytoplasmic;isocitrate dehydrogenase 1 (NADP+), soluble;NADP-dependent isocitrate dehydrogenase, cytosolic;NADP-dependent isocitrate dehydrogenase, peroxisomal;NADP(+)-specific ICDH;oxalosuccinate decarboxylase;PICD
Extra Details:: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence.

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