E-AB-22199
PPARD Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22199
- Additional Names:
- FAAR,MGC3931,NR1C2,NUC1,NUCI,NUCII,Nuclear hormone receptor 1,Nuclear receptor subfamily 1 group C member 2,Peroxisome proliferative activated receptor delta,Peroxisome proliferator-activated rec,Peroxisome proliferator-activated receptor beta (PPAR-beta)
- Application:
- IHC, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant Protein of PPAR Delta of PPAR Delta
- Clone:
- 1D7
- Uniprot:
- Q03181
- Synonyms:
- FAAR;NR1C2;NUC1;NUCI;NUCII;nuclear hormone receptor 1;nuclear receptor subfamily 1 group C member 2;peroxisome proliferator-activated receptor beta;peroxisome proliferator-activated receptor delta;PPAR-beta;PPAR-delta;PPARB;PPARD/MYO1D fusion
- Extra Details:
- This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and control the size and number of peroxisomes produced by cells. PPARs mediate a variety of biological processes, and may be involved in the development of several chronic diseases, including diabetes, obesity, atherosclerosis, and cancer. This protein is a potent inhibitor of ligand-induced transcription activity of PPAR alpha and PPAR gamma. It may function as an integrator of transcription repression and nuclear receptor signaling. The expression of this gene is found to be elevated in colorectal cancer cells. The elevated expression can be repressed by adenomatosis polyposis coli (APC), a tumor suppressor protein related to APC/beta-catenin signaling pathway.
- Shipping Conditions:
- Blue Ice