E-AB-22164
PI 3 kinase p85 alpha Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22164
- Additional Names:
- GRB1,P85A,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,p85,p85 alpha,polypeptide 1 (p85 alpha),regulatory subunit
- Application:
- IHC, WB, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant Protein
- Clone:
- 3B7
- Uniprot:
- P27986
- Synonyms:
- AGM7;GRB1;IMD36;p85;p85-ALPHA;phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;phosphatidylinositol 3-kinase regulatory subunit alpha;phosphatidylinositol 3-kinase-associated p-85 alpha;phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha);phosphoinositide-3-kinase regulatory subunit alpha;phosphoinositide-3-kinase, regulatory subunit 1 (alpha);PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;ptdIns-3-kinase regulatory subunit alpha
- Extra Details:
- Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
- Shipping Conditions:
- Blue Ice