E-AB-22144
TTR Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22144
- Additional Names:
- ATTR,Amyloid polyneuropathy,Amyloidosis I,CTS,CTS1,Carpal tunnel syndrome 1,Dysprealbuminemic euthyroidal hyperthyroxinemia,Dystransthyretinemic hyperthyroxinemia,Epididymis luminal protein 111,HEL111,HsT2651,PALB,Prealbumin,Prealbumin amyloidosis type I
- Application:
- IHC, WB, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant Protein of TTR
- Clone:
- 2A4
- Uniprot:
- P02766
- Synonyms:
- ATTR;CTS;CTS1;epididymis luminal protein 111;HEL111;HsT2651;PALB;Prealbumin;prealbumin, amyloidosis type I;TBPA;thyroxine-binding prealbumin;transthyretin;TTN
- Extra Details:
- This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
- Shipping Conditions:
- Blue Ice