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E-AB-22128

BAX Monoclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-22128
Additional Names:
Apoptosis regulator BAX,BAX,BAXA,BCL2 associated X protein,BCL2 associated X protein omega,BCL2 associated X protein transcript variant delta2,BCL2L4,Bax-protein,Baxdelta2G9,Baxdelta2G9omega,Baxdelta2omega,Bcl-2-like protein 4,Bcl2-L-4,membrane isofor
Application:
IHC, WB, IHC-P
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthetic Peptide of Bax
Clone:
1D8
Uniprot:
Q07812
Synonyms:
apoptosis regulator BAX;Baxdelta2G9;Baxdelta2G9omega;Baxdelta2omega;bcl-2-like protein 4;BCL2 associated X protein;BCL2-associated X protein omega;bcl2-L-4;BCL2L4
Extra Details:
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Shipping Conditions:
Blue Ice