E-AB-22127
ACTN1 Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22127
- Additional Names:
- ACTN 1,ACTN1,Actinin alpha 1,Actn1,Alpha Actinin 1,Alpha actinin cytoskeletal isoform,Alpha-actinin cytoskeletal isoform,Alpha-actinin-1,BDPLT15,F,F actin cross linking protein,F-actin cross-linking protein,FLJ40884,actinin,actinin 1 smooth muscle,alpha 1
- Application:
- IHC, IHC-P
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Recombinant Protein of a-actinin of ACTN1
- Clone:
- 1D4
- Uniprot:
- P12814
- Synonyms:
- actinin 1 smooth muscle;Alpha-actinin cytoskeletal isoform;alpha-actinin-1;BDPLT15;epididymis secretory sperm binding protein;F-actin cross-linking protein;non-muscle alpha-actinin-1
- Extra Details:
- Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice