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E-AB-22101

ITGA2B Monoclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-22101
Additional Names:
BDPLT16,BDPLT2,CD41,CD41B,GP2B,GPIIb,GPalpha IIb,GT,GTA,HPA3,ITA2B,ITGAB,Integrin,Integrin alpha 2b,Integrin alpha IIb,Integrin alpha-IIb light chain,Itga2b,alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex,antigen CD41,antigen CD41),form 2,platelet
Application:
IHC, IHC-P
Concentration:
1 mg/ml
Purification:
Protein A Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Mouse
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:
Synthetic Peptide
Clone:
5D1
Uniprot:
P08514
Synonyms:
alphaIIb protein;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPalpha IIb;GPIIb;GT;GT1;GTA;HPA3;integrin alpha-IIb;integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41);platelet fibrinogen receptor, alpha subunit;platelet glycoprotein IIb of IIb/IIIa complex;platelet membrane glycoprotein IIb;platelet-specific antigen BAK;PPP1R93;protein phosphatase 1, regulatory subunit 93
Extra Details:
ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.
Shipping Conditions:
Blue Ice