E-AB-22086
Histone H2B Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22086
- Additional Names:
- (testis specific),H2B,H2B histone family,H2B histone family member U,H2B histone family member U testis specific,H2B testis,H2B1A,H2BFU,H2BT,H2ba,HIST1H2BA,Histone 1,Histone H2B,Histone H2B testi,Histone cluster 1 H2ba,bA317E16.3,member U,testis
- Application:
- WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthetic Peptide
- Clone:
- 3C3
- Uniprot:
- P33778
- Synonyms:
- H2B histone family, member F;H2B.1;H2B/f;H2BFF;HIST1H2BB;histone 1, H2bb;histone cluster 1 H2B family member b;histone cluster 1, H2bb;histone H2B type 1-B;histone H2B.1;histone H2B.f
- Extra Details:
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3. HIST1H2BB (Histone Cluster 1 H2B Family Member B) is a Protein Coding gene. Among its related pathways are DNA Double-Strand Break Repair and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is HIST1H2BN.
- Shipping Conditions:
- Blue Ice