PARP1 Monoclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-22073
Additional Names:: ADP-ribosyltransferase diphtheria toxin-like 1,ADPRT,ADPRT 1,ADPRT1,APOPAIN,ARTD1,NAD(+) ADP-ribosyltransferase 1,PARP,PARP-1,PARP1,PPOL,Poly ADP ribose polymerase 1,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,SCA1
Application:: WB
Concentration:: 1 mg/ml
Purification:: Protein A Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
Immunogen:: Synthetic Peptide
Clone:: 1L5
Uniprot:: P09874
Synonyms:: ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase);ADP-ribosyltransferase diphtheria toxin-like 1;ADP-ribosyltransferase NAD(+);ADPRT;ADPRT 1;ADPRT1;ARTD1;DNA ADP-ribosyltransferase PARP1;NAD(+) ADP-ribosyltransferase 1;pADPRT-1;PARP;PARP-1;poly (ADP-ribose) polymerase family, member 1;poly [ADP-ribose] polymerase 1;poly(ADP-ribose) synthetase;poly(ADP-ribosyl)transferase;poly[ADP-ribose] synthase 1;PPOL;protein poly-ADP-ribosyltransferase PARP1
Extra Details:: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

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