E-AB-22044
XRCC4 Monoclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-22044
- Additional Names:
- DNA double strand break repair and V(D)J recombination protein XRCC4,DNA repair protein XRCC4,SSMED,X ray repair complementing defective repair in Chinese hamster cells 4,X ray repair cross complementing 4,X ray repair cross complementing protein 4,X-ray
- Application:
- IHC, WB, IHC-P, IF, IP
- Concentration:
- 1 mg/ml
- Purification:
- Protein A Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Mouse
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthetic Peptide
- Clone:
- 8K2
- Uniprot:
- Q13426
- Synonyms:
- DNA repair protein XRCC4;SSMED;X-ray repair complementing defective repair in Chinese hamster cells 4;X-ray repair cross-complementing protein 4
- Extra Details:
- Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
- Shipping Conditions:
- Blue Ice