E-AB-20287
Acetyl-P53 (Lys381) Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-20287
- Additional Names:
- Antigen NY-CO-13,BCC7,Cellular tumor antigen p53,FLJ92943,LFS1,Mutant tumor protein 53,P53,Phosphoprotein p53,TRP53,Tp53,Transformation related protein 53,Tumor protein 53,Tumor protein p53,Tumor suppressor p53,p53,p53 tumor suppressor
- Application:
- IHC, WB, IHC-P, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol.
- Immunogen:
- Synthesized peptide derived from human p53 around the acetylation site of K381
- Uniprot:
- P04637
- Synonyms:
- antigen NY-CO-13;BCC7;BMFS5;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;Tumor suppressor p53;tumor supressor p53
- Extra Details:
- The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
- Shipping Conditions:
- Blue Ice