E-AB-19973
GTF3A Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19973
- Additional Names:
- AP 2,AP2,Factor A,GTF 3A,GTF3A,General transcription factor 3A,General transcription factor IIIA,TF3A,TFIIIA,Transcription factor 3A,Transcription factor IIIA
- Application:
- IHC, WB
- Concentration:
- 1.68 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human GTF3A
- Uniprot:
- Q92664
- Synonyms:
- AP2;TFIIIA;transcription factor IIIA
- Extra Details:
- The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein.
- Shipping Conditions:
- Blue Ice