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E-AB-19960

GPSM2 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19960
Additional Names:
DFNB82,G protein signalling modulator 2,G protein signalling modulator 2 (AGS3 like C. elegans),G-protein-signaling modulator 2,GPSM2,Gpsm2,HGNC:29501,LGN,LGN protein,Mosaic protein LGN,Pins
Application:
IHC
Concentration:
1.92 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human GPSM2
Uniprot:
P81274
Synonyms:
CMCS;DFNB82;G-protein signalling modulator 2 (AGS3-like, C. elegans);G-protein-signaling modulator 2;LGN;mosaic protein LGN;PINS
Extra Details:
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses.The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange.This protein may play a role in neuroblast division and in the development of normal hearing.Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice