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E-AB-19878

FOLR1 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:
E-AB-19878
Additional Names:
Adult folate binding protein,Adult folate-binding protein,FBP,FOLR,FOLR1,FR alpha,FR-alpha,FRalpha,Folate Receptor 1 Adult,Folate Receptor 1 Precursor,Folate receptor,Folate receptor 1,Folate receptor adult,Folate receptor alpha,KB cells FBP,M,adult
Application:
IHC
Concentration:
2.28 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human FOLR1
Uniprot:
P15328
Synonyms:
adult folate-binding protein;FBP;folate binding protein;Folate receptor 1;folate receptor 1 (adult);folate receptor alpha;folate receptor, adult;FOLR;FR-alpha;FRalpha;KB cells FBP;NCFTD;ovarian tumor-associated antigen MOv18
Extra Details:
Folate receptor 1 (FOLR1),also known as folate receptor alpha or adult folate-binding protein (FBP),is a 38-kDa glycoprotein belonging to the folate receptor family . The receptor binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells. FOLR1 is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. FOLR1 expression is often limited to the apical surfaces of epithelium in the lung,kidney and choroid plexus but is differentially overexpressed in a variety of solid tumors such as ovarian cancer,non-small cell lung cancer,breast cancer,kidney cancer and high-grade osteosarcoma .
Shipping Conditions:
Blue Ice