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E-AB-19860

CTDP1 Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19860
Additional Names:
RNA polymerase II, phosphatase of, polypeptide A) phosphatase, subunit 1,CCFDN,CTD (carboxy-terminal domain,CTD of POLR2A,CTDP1,EC 3.1.3.16 ,RNA polymerase II subunit A C terminal domain phosphatase,RNA polymerase II subunit A C-terminal
Application:
IHC
Concentration:
2.16 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human CTDP1
Uniprot:
Q9Y5B0
Synonyms:
CCFDN;CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1;CTD of POLR2A, phosphatase of, subunit 1;FCP1;RNA polymerase II subunit A C-terminal domain phosphatase;serine phosphatase FCP1a;TFIIF-associating CTD phosphatase;TFIIF-associating CTD phosphatase 1;transcription factor IIF-associating CTD phosphatase 1
Extra Details:
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression.Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN).Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Shipping Conditions:
Blue Ice