E-AB-19833
ACOD1 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19833
- Additional Names:
- ACOD1,Aconitate decarboxylase,Aconitate decarboxylase 1,CAD,Cis aconitate decarboxylase,IRG1,Immune responsive gene 1 protein homolog,Immune-responsive gene 1 protein homolog,Immunoresponsive 1 homolog (mouse),Irg1,OC116,OPTB1,TCTIRC7
- Application:
- WB
- Concentration:
- 1.32 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ACOD1
- Uniprot:
- A6NK06
- Synonyms:
- Aconitate decarboxylase;Aconitate decarboxylase 1;CAD;cis-aconitate decarboxylase;cis-aconitic acid decarboxylase;Immune-responsive gene 1 protein;immune-responsive gene 1 protein homolog;immunoresponsive 1 homolog;IRG1
- Extra Details:
- Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells, ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation.
- Shipping Conditions:
- Blue Ice