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IL12B Polyclonal Antibody

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E-AB-19816

IL12B Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19816
Additional Names:
IL-12/IL-23 p,IL-12 subunit p,NK cell stimulatory factor chain,NK cell Stimulating Factor Chain,CLMF p,IMD,IL12B,CLMF,CLMF2,IL-12B,IMD28,IMD29,NKSF,NKSF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40),IL-12/IL-23 p40,NK cell Stimulating Factor Chain 2,p40,Interleukin-12 subunit beta,CLMF p40,IL-12 subunit p40,NK cell stimulatory factor chain 2,IL 12B,IL12 p40,Interleukin 12 beta chain,Interleukin 12 p40
Application:
IHC
Concentration:
1.32 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human IL12B
Uniprot:
P29460
Synonyms:
CLMF;CLMF p40;CLMF2;cytotoxic lymphocyte maturation factor 40 kDa subunit;IL-12 subunit p40;IL-12B;IL12, subunit p40;IMD28;IMD29;interleukin 12, p40;interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40);interleukin-12 beta chain;interleukin-12 subunit beta;natural killer cell stimulatory factor, 40 kD subunit;NK cell stimulatory factor chain 2;NKSF;NKSF2
Extra Details:
Interleukin-12 (IL-12),is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-G Gammaproduction by natural-killer and T lymphocytes. IL-12 is a 75 kDa heterodimer composed of a 35 kDa subunit (IL-12A p35) and a 40 kDa subunit (IL-12B p40) that is secreted by a wide variety of antigen presenting cells (APCs),including phagocytes,B cells and Langerhans cells. IL-12B has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of IL-12B was observed in the central nervous system of patients with multiple sclerosis (MS),suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12B has been reported to be associated with the severity of atopic and non-atopic asthma in children.
Shipping Conditions:
Blue Ice