E-AB-19794
EBF2 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19794
- Additional Names:
- COE 2,COE2,Collier Olf and EBF 2,EBF 2,EBF-2,Early B cell factor 2,Early B-cell factor 2,Ebf2,FLJ11500,Metencephalon mesencephalnon olfactory transcription factor 1,O/E 3,O/E3,OE 3,OE3,OLF 1/EBF like 3,Transcription factor COE2
- Application:
- WB
- Concentration:
- 1.68 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human EBF2
- Uniprot:
- Q9HAK2
- Synonyms:
- COE2;Collier, Olf and EBF 2;Collier, Olf and EBF transcription factor 2;early B cell factor 2;Early B-cell factor 2;EBF-2;metencephalon-mesencephalnon-olfactory transcription factor 1;O/E-3;OE-3;OLF-1/EBF-LIKE 3;transcription factor COE2
- Extra Details:
- The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.
- Shipping Conditions:
- Blue Ice