E-AB-19785
FBXO32 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19785
- Additional Names:
- 4833442G10Rik,AI430017,ATROGIN1,Atrogin 1 ,Atrogin-1,Atrophy gene 1,F box only protein 32,F-box only protein 32,F-box protein 32,FBX32,FBXO32,FLJ32424,MAFbx,MGC108443,MGC137646,MGC33610 ,Muscle atro,Muscle atrophy F box,Muscle atrophy F box protein,fbxo25
- Application:
- IHC
- Concentration:
- 1.44 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human FBXO32
- Uniprot:
- Q969P5
- Synonyms:
- atrogin 1;Atrogin-1;F-box only protein 32;Fbx32;MAFbx;muscle atrophy F-box protein
- Extra Details:
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice