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E-AB-19759

PNPO Polyclonal Antibody

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£106.20

Was £118.00

SKU:
E-AB-19759
Additional Names:
EC 1.4.3.5,FLJ10535,PDXPO,PNPO,Pyridoxal 5' phosphate synthase,Pyridoxamine phosphate oxidase ,Pyridoxamine-phosphate oxidase,Pyridoxine-5'-phosphate oxidase,pyridoxamine 5' phosphate oxidase,pyridoxine 5' phosphate oxidase
Application:
IHC, WB
Concentration:
0.9 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human PNPO
Uniprot:
Q9NVS9
Synonyms:
epididymis secretory protein Li 302;epididymis secretory sperm binding protein;HEL-S-302;PDXPO;pyridoxal 5'-phosphate synthase;pyridoxamine-phosphate oxidase;pyridoxine 5'-phosphate oxidase;pyridoxine-5'-phosphate oxidase
Extra Details:
The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine. Mutations in this gene result in pyridoxamine 5'-phosphate oxidase (PNPO) deficiency, a form of neonatal epileptic encephalopathy.
Shipping Conditions:
Blue Ice