E-AB-19682
CDH12 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19682
- Additional Names:
- BR-cadherin,Br cadherin,Brain cadherin,CAD12_HUMAN,CDH12,CDHB,Cadherin 12,Cadherin 12 precursor,Cadherin 12 type 2,Cadherin 12 type 2 (N cadherin 2),Cadherin neural type 2,Cadherin-12,FLJ34857,N cadherin 2,N-cadherin 2,Neural ty,cadherin 12 (N cadherin 2)
- Application:
- IHC
- Concentration:
- 1.74 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CDH12
- Uniprot:
- P55289
- Synonyms:
- Br-cadherin;Brain cadherin;brain-cadherin;cadherin-12;cadherin, neural type, 2;CDHB;N-cadherin 2;neural type cadherin 2;neuronal cadherin 2
- Extra Details:
- This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.
- Shipping Conditions:
- Blue Ice