E-AB-19667
CBFA2T3 Polyclonal Antibody
Size
£106.20
Was £118.00
- SKU:
- E-AB-19667
- Additional Names:
- Cbfa2t3,Ccore binding factor runt domain alpha subunit 2 translocated to 3,ETO2,MTG16,MTG8 related gene 2,MTG8 related protein MTG16a,MTG8 related protein MTG16b,MTG8-related protein 2,MTGR2,Myeloid translocation gene 8 and 16,hMTG16,hMTG16a,hMTG16b
- Application:
- IHC
- Concentration:
- 1.1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CBFA2T3
- Uniprot:
- O75081
- Synonyms:
- CBFA2/RUNX1 translocation partner 3;core-binding factor, runt domain, alpha subunit 2; translocated to, 3;ETO2;MTG16;MTG8-related gene 2;MTG8-related protein 2;MTGR2;myeloid translocation gene 8 and 16b;myeloid translocation gene on chromosome 16 protein;protein CBFA2T3;RUNX1T3;zinc finger MYND domain-containing protein 4;ZMYND4
- Extra Details:
- This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16,21)(q24,q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.
- Shipping Conditions:
- Blue Ice