CAPN9 Polyclonal Antibody

Size

£106.20

Was £118.00

SKU:: E-AB-19659
Additional Names:: CAN9,CAPN 9,CAPN9,CG36 protein,Calpain-9,Calpain9,Digestive tract specific calpain,Digestive tract-specific calpain,GC36,New calpain 4,OTTHUMP00000035899,OTTHUMP00000035900,Protein CG36,nCL-4,nCL4,novel calpain large subunit-4,novel calpain large subunit4
Application:: IHC
Concentration:: 0.5 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Synthetic peptide of human CAPN9
Uniprot:: O14815
Synonyms:: calpain-9;digestive tract-specific calpain;GC36;nCL-4;new calpain 4;novel calpain large subunit-4;Protein CG36
Extra Details:: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This gene is thought to be associated with gastric cancer. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.CAPN9 (Calpain 9) is a Protein Coding gene. Diseases associated with CAPN9 include Gastric Cancer. Among its related pathways are Degradation of the extracellular matrix and Arrhythmogenic right ventricular cardiomyopathy (ARVC). GO annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPN3.

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